Phineas Gage was an American railroad worker famous for surviving a renowned accident. An explosion drove a large iron rod, or tampering spike, entirely through his head, destroying much of his brain's left frontal lobe and blinding him in his left eye.
His injuries reportedly affected his personality and behavior over the remaining 12 years of his life. While some reports may have been exaggerated, the case of Phineas Gage remains one of the most famous in the history of Neuroscience.
See how his injury occurred in this 3d animation video.
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